Process for the preparation of 6-amino-nicotinonitriles

Details Process for the preparation of 6-amino-nicotinonitriles Process for the preparation of 6-amino-nicotinonitriles

1994-01-11

1996-01-02

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546193, 546289, 544124, 544360, C07D21309, C07D21385, C07D40102, C07D41302

Patent

active

054809959

ABSTRACT:
6-Amino-nicotinonitriles of the formula ##STR1## can be prepared by reacting methylene-glutacononitriles of the formula ##STR2## with nitrogen compounds of the formula

REFERENCES:
patent: 4405552 (1983-09-01), Miesel
patent: 4849432 (1989-07-01), Shiokawa et al.
F. Scotti et al., J. Org. Chem., 29, 1800 (1964).
Science, Oct. 3, 1969, vol. 166, No. 3901; "Photochemical reactions and the chemical evolution of purines and nicotinamide derivatives", J. P. Ferris et al; cover page and pp. 765-766.
(Abstract) [JP] Japanese Patent 099595 pub. Nov. 15, 1986.
The Chemistry of Heterocyclic Compounds, Part 5, pp. 118-141, 227-231, (1979).
J. Chem. Soc. pp. 5542-5551 (1965).

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