Process for the preparation of N,N-dimethyl-10-[1-aza-[2,2,2]-bi

Details Process for the preparation of N,N-dimethyl-10-[1-aza-[2,2,2]-bi Process for the preparation of N,N-dimethyl-10-[1-aza-[2,2,2]-bi

1982-08-02

1984-11-13

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D41700

Patent

active

044827113

ABSTRACT:
Process for the preparation of N,N-dimethyl-10[1-aza-[2,2,2]-bicyclo-3-octyl]-10H-2-phenothiazine sulphonamide, usable as a gastric secretion inhibitor, characterized in that N,N-dimethyl-3-[(1-aza-[2,2,2]-bicyclo-3-octyl)amino]-4-[(2-bromophenyl)th io] benzene sulphonamide is cyclized in the presence of an alkali metal amide.

REFERENCES:
patent: 2909521 (1959-10-01), Jacob et al.
patent: 3534053 (1970-10-01), Sallay et al.
patent: 3563995 (1971-02-01), Wellings
patent: 3987042 (1976-10-01), Gueremy et al.
Theilheimer, Synthetic Methods Org. Chem. 22 p. 230 No. 531 (1968).

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