Process for the preparation of a 4,5-tri or tetramethylene-4-iso

Details Process for the preparation of a 4,5-tri or tetramethylene-4-iso Process for the preparation of a 4,5-tri or tetramethylene-4-iso

1986-06-05

1989-07-25

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

564189, 564191, C07D27504

Patent

active

048515418

ABSTRACT:
A process for preparing a 4,5-tri or tetramethylene-4-isothiazoline-3-one comprises cyclizing a 2-alkyl or aralkyl thio-1-cycloalkene-1-carboxamide in the form of its sulfoxide in an organic solvent in the presence of a acid chloride and adding to the resulting 4,5-tri or tetramethylene-4-isothiazoline-3-one hydrochloride a mineral or organic base or water so as to free the 4,5-tri or tetramethylene-4-isothiazoline-3-one in the form of a free base.

REFERENCES:
patent: 2767172 (1956-10-01), Katz et al.
patent: 3012039 (1961-12-01), Morley
patent: 3227715 (1966-01-01), Bub
patent: 3300378 (1967-01-01), Fischer
patent: 3362992 (1968-01-01), Schwartz
patent: 3661974 (1972-05-01), Grivas
patent: 4708959 (1987-11-01), Shroot et al.
Uchida et al, JCS Chem Comm., vol. of 1981, No. 10, pp. 510 and 511.
Baeckvall et al, Chemical Abstract, vol. 99, #176022s (1983).
Beak et al, J. Amer. Chem. Soc., vol. 107, pp. 4745 to 4756 (1985).
Huisgen et al, Chemical Abstracts, vol. 64, #9711-9712 (1966).

Affiliated with

Also associated with

Rating

Process for the preparation of a 4,5-tri or tetramethylene-4-iso does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of a 4,5-tri or tetramethylene-4-iso, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of a 4,5-tri or tetramethylene-4-iso will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2359332