Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1995-04-27
1996-10-22
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 31135
Patent
active
055677339
ABSTRACT:
A method of relieving irritation to a patient's mucous membrane is provided and comprises contacting the mucous membrane with a non-steroidal anti-inflammatory agent, such as diclofenac sodium, that may be instilled as a spray of drop-wise into the nasopharynx mucosa. The same methodology can also be employed to relieve irritation of a patient's nasopharynx mucosa resulting from anesthesia by endotracheal intubation. A method of administering anesthesia in order to reduce irritation of the tracheal mucosa is also provided and comprises the steps of instilling a quantity of diclofenac sodium solution into the patient's tracheal mucosa, allowing the diclofenac sodium to operate for a selected interval of time, intubating the patient with an anesthesia delivery tube after this interval of time, and delivering a selected anesthesia to the patient.
REFERENCES:
patent: 5234957 (1993-08-01), Mantelle
patent: 5458879 (1995-10-01), Singh et al.
patent: 5464609 (1995-11-01), Kelm et al.
Martindale, The Extra Pharmacopoeia, 30th edition, p. 998. 1993.
"Human Transbuccal Absorption of Diclofenac Sodium from a Proto-type Hydrogel Delivery Device", Pharmaceutical Research, vol. 10, No. 1 (1993).
Henley III Raymond
Henson Michael R.
Martin Timothy J.
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