Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-12-06
1997-10-07
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 435 71, C12Q 168, C12P 1934, G01N 3353
Patent
active
056746814
ABSTRACT:
The present invention provides methods to identify hemochromatosis in an individual. For example, the invention provides a method of detecting reduced association of .beta..sub.2 -microglobulin with a nonclassical MHC class I heavy chain molecule or a mutation in nonclassical MHC class I heavy chain-encoding DNA which results in a reduction of .beta..sub.2 -microglobulin-heavy chain association indicating that the individual tested has or is at risk of having hemochromatosis.
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