Novel process for the preparation of pyrazoles from isoxazoles

Details Novel process for the preparation of pyrazoles from isoxazoles Novel process for the preparation of pyrazoles from isoxazoles

1989-02-13

1990-05-08

Lee, M. C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548213, 548214, 548240, 548243, 548247, 548248, 548356, 548375, 548378, 548379, C07D23120, C07D23112

Patent

active

049240021

ABSTRACT:
The present invention is a process in which isoxazoles are treated with Mo(CO).sub.6 and then hydrazine to obtain corresponding pyrazoles.

REFERENCES:
patent: 4691015 (1987-09-01), Behrens et al.
J. Chem. Soc. Chem. Commun., 1982, "Reductive Ring Opening of Isoxzoles with Mo(CO).sub.6 and Water" Nitta and Kobayashi, pp. 877 & 878.
Tetrahendron Letters, vol. 26, No. 43, pp. 5319-5322, 1985 Pergamon Press Ltd., "A New Nitrile Oxide Based Synthesis of the Antitumor Agent Geiparvarin" Pier Giovanni Varaldi, et al.

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