Pyrindamycins A and B and duocarmycin A antibiotics derived from

Details Pyrindamycins A and B and duocarmycin A antibiotics derived from Pyrindamycins A and B and duocarmycin A antibiotics derived from

1988-09-09

1990-05-08

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548421, 435119, C07D48704, C07D51900, C07_51900, C12P 1718

Patent

active

049239902

ABSTRACT:
The present invention relates to DC-88A and DC-89A1 and their production. These compounds are obtained by fermentation of microorganisms belonging to the genus Streptomyces. These compounds have antibacterial and anti-tumor activities and are useful as medicaments.

REFERENCES:
patent: 4169888 (1969-10-01), Hanka et al.
patent: 4400518 (1983-08-01), Wieringa
patent: 4413132 (1983-11-01), Wieringa
patent: 4423228 (1983-12-01), Wieringa
patent: 4423229 (1983-12-01), Wieringa
patent: 4423230 (1983-12-01), Wieringa
Adv. Enzyme Regul. 25, 141-155 (1986), Wieringa, et al., "Antitumor Activity . . . ".
J. Med. Chem. 31, 590-603 (1988), Warpehoski et al., "Stereo Electronic Factors . . . ".

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