Morpholine derivatives, pharmaceutical compositions and use

Details Morpholine derivatives, pharmaceutical compositions and use Morpholine derivatives, pharmaceutical compositions and use

1989-06-06

1990-05-08

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142368, 5142375, 544131, 544137, 544141, 544162, 544167, A61K 31535, C07D26530, C07D41306

Patent

active

049238639

ABSTRACT:
Compounds are disclosed of formula (I): ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and are C.sub.1-6 alkyl or C.sub.3-6 alkenyl; or --NR.sub.1 R.sub.2 forms a 5-membered (optionally containing an oxygen atom adjacent to the nitrogen) or a 6-membered ring, which ring optionally contains one unit of unsaturation and which is unsubstituted or substituted by hydroxy, oxo, optionally substituted methylidene, --COR.sub.3 (where R.sub.6 represents C.sub.1-6 alkyl, OR.sub.4 or --NHR.sub.4, and R.sub.4 represents hydrogen, C.sub.1-6 alkyl, aryl, ar(C.sub.1-6)alkyl) or .dbd.NOR.sub.5 (where R.sub.5 represents C.sub.1-6 alkyl);

REFERENCES:
patent: 2428239 (1947-09-01), Parker et al.
patent: 3586713 (1971-06-01), Buu-Hoi et al.

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