Bonding enzymes to porous inorganic carriers

Textiles: fiber preparation

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195 68, 195DIG11, C07G 702

Patent

active

039309517

ABSTRACT:
Enzymes can be coupled chemically to various water-insoluble inorganic carriers by reacting the carriers with 4,4'-bi(methoxybenzenediazonium chloride) to form a surface of diazo groups which are subsequently reacted with an enzyme solution to immobilize the enzymes. In preferred embodiments, the inorganic carriers are highly porous, have an average pore size of less than about 1000 A, and consist of 4-200 mesh porous particles of materials selected from the group consisting of glass, silica, alumina, and mixtures of silica and alumina.

REFERENCES:
patent: 2968635 (1961-01-01), Nixon
patent: 3666627 (1972-05-01), Messing
patent: 3669841 (1972-06-01), Miller
patent: 3705084 (1972-12-01), Reynolds
patent: 3783101 (1974-01-01), Tomb et al.
patent: 3804719 (1974-04-01), Messing
Zaborsky, O., Immobilized Enzymes, The Chemical Rubber Co., Cleveland, Ohio, 1973. (pp. 61, 62, 70, 72 & 73).

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