Antihypertensive tetrahydropyridine 3,5 dicarboxylic acid esters

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514333, 514338, 514356, 546256, 546263, 546270, 546321, C07D21178, C07D40112, C07D40502, A61K 31455

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active

045686815

ABSTRACT:
1,2,3,4-Tetrahydropyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heterocyclic,

REFERENCES:
Chatterjea, J. N., "1,3-Dimethy1-2-Azafluorenore Meyer's Pyridine Synthesis", Chemical Abstracts 47:9972.
Bossert, F. et al., "4-Aryldihydropyridines", Angew. Chem. Int. Ed. Engl. 20, pp. 762-769 (1981).
Schramm, M. et al., "Novel Dihydropyridines with Positive Inotropic Action Through Activation of Ca.sup.2+ Channels", Nature, vol. 303, (Jun. 9, 1983), pp. 535-537.

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