Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-09-19
2000-04-18
Kemmerer, Elizabeth
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 681, 435 694, 435 697, 435 698, 530308, 530324, 530345, 536 234, C12P 2100, C07K 1446, C07H 2104
Patent
active
060513993
ABSTRACT:
A method for the production of C-terminal amidated recombinant peptides is provided. The method employs a recombinant protein construct having multiple copies of a target peptide linked by intraconnecting peptides. The intraconnecting peptides permit the multicopy construct to be selectively reacted to produce product peptides having a C-terminal .alpha.-carboxamide. A recombinant gene containing a DNA sequence coding for the recombinant protein construct and an expression cassette, an expression vector and a transformed cell including the recombinant gene are also provided.
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Henriksen Dennis B.
Holmquist Barton
Partridge Bruce E.
Stout Jay S.
Wagner Fred W.
BioNebraska, Inc.
Kemmerer Elizabeth
Romeo David
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