Cyclic peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides

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A61K 3812

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active

056333455

ABSTRACT:
To provide a process for the total synthesis of a cyclic peptide, which is useful as antifungal drug, and novel compounds prepared by the synthesis method. A process for synthesizing a cyclic peptide represented by the following formula (I): ##STR1## wherein X1, X2, X4 and X7 are independently N-methyl-.alpha.-amino acid or .alpha.-hydroxy acid,

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Chemistry Letters, Kurome et al., "Total Synthesis of Aureobasidin A, an Antifungal Cyclid Depsipeptide", vol. 11, pp. 1873-1876 (1993).

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