2-alkenyloxy-3-(phosphono)oxypropanoic acids derived from the cl

Details 2-alkenyloxy-3-(phosphono)oxypropanoic acids derived from the cl 2-alkenyloxy-3-(phosphono)oxypropanoic acids derived from the cl

1992-08-11

1993-04-27

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

C07F 909

Patent

active

052064050

ABSTRACT:
A new Bacillus species and the appropriate enzymes obtained therefrom can be used to break down phosphoglycolipid antibiotics. The breakdown products of moenomycins display antibiotic activity or can be used as building blocks for the synthetic preparation of transglycosylase inhibitors.

REFERENCES:
patent: 4684626 (1978-08-01), Welzel et al.
Welzel, P. Tetrahedron Lett. 1976(20), 1665-1668.
Takahashi, S. Tetrahedron Lett. 24(5), 499-502 (1983).
Fehlhaber et al., "Moenomycin A: A Structural Revision And New Structure-Activity Relations," Tetrahedron, vol. 46(5):1557-1568 (1990).

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