Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1993-11-16
1997-05-27
Crouch, Deborah
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
800 2, 935 52, 935 53, C12N 1500, C12N 500
Patent
active
056330766
ABSTRACT:
A method is disclosed for the production of a transgenic bovine or a transgenic bovine embryo comprising obtaining an ovum from bovine ovaries, maturing the ovum in vitro, fertilizing the mature ovum or ova in vitro to form a zygote, introducing a transgene into the zygote in vitro and maturing the zygote to a preimplantation stage embryo in vitro. To produce the transgenic bovine, the embryo is transplanted into a recipient female bovine, wherein the female bovine gestates the embryo to produce a transgenic bovine.
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Denman et al. "
DeBoer Herman A.
Heyneker Herbert L.
Krimpenfort Paul J. A.
Lee Sang H.
Pieper Frank
Crouch Deborah
Pharming BV
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