Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-09-03
1997-01-21
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4352402, 4353201, 935 77, 935 78, 536 231, C12Q 170, C07H 2102, C12N 1579, C12N 510
Patent
active
055958729
ABSTRACT:
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
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Biller Scott A.
Dickson John K.
Gregg Richard E.
Holava Henry M.
Lawrence R. Michael
Bogden James M.
Bristol--Myers Squibb Company
Gaul Timothy J.
Zitomer Stephanie W.
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