Carbocyclic analogues of amino and azido thymidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544312, C07D23926, A61K 31505

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active

047300019

ABSTRACT:
There are disclosed compounds represented by Formulas I-III: ##STR1## wherein X is an azido group or an amino group and R is hydrogen or an acyl group. These compounds are useful for the treatment of viral infections and/or as intermediates in the production of compounds which are useful in the treatment of viral infections.

REFERENCES:
patent: 4396623 (1983-08-01), Shealy
Chemical Abstracts, vol. 104 (1986), p. 733, Entry Nos. 130206y and 130207z.
Shealy and Clayton, Journal of the American Chemical Society, vol. 88, pp. 3885-3887, 1966.
C. Desgranges et al, Biochemical Pharmacology, vol. 32, pp. 3583-3590, 1983, Horwitz et al, J. Org. Chem., pp. 3045-3048, 1962.
Neenan et al, J. Med. Chem., pp. 580-581, 1973.
Cheng et al, Biochemistry, pp. 1179-1185, 1974.
Cheng et al., Biochemistry, pp. 2612-2619, 1973.
Chen et al, Antimicrob. Agents Chemother., pp. 433-436, 1980.
Letsinger et al, J. Am. Chem. Soc., pp. 292-293, 1972.
Lin et al, J. Med. Chem., pp. 495-498, 1976.
Lin et al, J. Med. Chem., pp. 109-112, 1978.
Miller et al, J. Org. Chem., pp. 1772-1776, 1964.
Horwitz et al, J. Org. Chem., pp. 2076-2078, 1964.
Matsuda et al, J. Org. Chem., pp. 3274-3278, 1980.
Lin et al, Biochem. Pharmacol., pp. 125-128, 1982.
Chen et al, Molecular Pharmacol., pp. 441-445, 1984.
Shealy et al, Journal of Heterocyclic Chemistry, vol. 20, pp. 655-661, 1983.
Shannon et al, Antimocrob. Agents Chemother., pp. 769-776, 1981.

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