Piperazine and piperidine enamines having an hydroxy group

Details Piperazine and piperidine enamines having an hydroxy group Piperazine and piperidine enamines having an hydroxy group

1978-04-21

1979-05-29

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544386, 544402, 546247, C07D21108, C07D24104

Patent

active

041567790

ABSTRACT:
What is disclosed is the method of making a monoenamine having a free hydroxy group which comprises reacting a lactone or a carboxylic acid containing an hydroxy group with an amine selected from the group consisting of 2-methyl piperazine, 1-(2-aminoethyl)-piperazine, 4-aminomethyl-piperidine, or 2,3-dimethyl-3-(gamma-aminopropyl)-piperidine to form the corresponding secondary amine containing an hydroxy group and then reacting said secondary amine with an aliphatic aldehyde or cyclic ketone to form said monoenamine.

REFERENCES:
patent: 3250794 (1966-05-01), Mod
patent: 3357978 (1967-12-01), Thominet
patent: 3865791 (1975-02-01), Brinkmann
Wagner et al., "Synthetic Organic Chemistry," Wiley and Sons, Inc., N. Y., 1953, p. 567.

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