Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1992-02-11
1993-07-13
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 71, C07C 6988
Patent
active
052275140
ABSTRACT:
Salicylic acid esters of carnitine are distinguished relative to acetylsalicylic acid by high water solubility, low toxicity and good stomach tolerance. The compounds are obtainable in three stages from carnitine hydrochloride and o-methoxybenzoyl chloride.
REFERENCES:
patent: 4271310 (1981-06-01), Watanabe
patent: 4336400 (1982-06-01), Minatoya et al.
Okabe et al., Japan. J. Pharmacol., 24, (1974), pp. 363 to 371.
Chaumontet et al., Arzneimittelforschung [Pharmaceutical Agent Research], 28, (1978), pp. 2119 to 2121.
Deshusses Jacques
Meul Thomas
Killos Paul J.
Lonza Ltd.
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