Stable hydrophilic acridinium esters suitable for liposome encap

Details Stable hydrophilic acridinium esters suitable for liposome encap Stable hydrophilic acridinium esters suitable for liposome encap

1992-01-22

1993-07-13

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

534751, 534798, 546102, 546104, 546107, 424450, 436172, 435 5, C07D21904

Patent

active

052274896

ABSTRACT:
A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesicles without significant leakage of the esters from the vesicles. The lumisomes can be coupled to molecules with biological activity, such as antigens, antibodies, and nucleic acids, and used in luminescent assays.

REFERENCES:
patent: 3352791 (1967-11-01), Sheehan et al.
patent: 3689391 (1972-09-01), Ullman
patent: 4745181 (1988-05-01), Law et al.
patent: 4918192 (1990-04-01), Law et al.
patent: 4933121 (1990-06-01), Law et al.
patent: 4946958 (1990-08-01), Campbell et al.
patent: 4950613 (1990-08-01), Arnold, Jr. et al.
patent: 5094785 (1992-03-01), Law et al.
patent: 5110932 (1992-05-01), Law et al.
McCapra et al., Chemical Abstracts, vol. 112(23):213573g, (1989).
Martinet et al., Bull. Soc. Chim. Fr., vol. 45, pp. 101-109, (1929).
Meek et al., J. Chem. Eng. Data, vol. 14, pp. 388-391, (1969).

Affiliated with

Also associated with

Rating

Stable hydrophilic acridinium esters suitable for liposome encap does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stable hydrophilic acridinium esters suitable for liposome encap, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable hydrophilic acridinium esters suitable for liposome encap will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2313104