Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic

Details Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic

1985-03-27

1986-08-26

Lone, Werren B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514511, 514557, 514703, 514729, 560119, C07C 6974

Patent

active

046083880

ABSTRACT:
Compounds useful in treating cardiovascular disorders such as thrombosis, hypertension, and atherosclerosis are compounds depicted in formulas (1), (2), and (3): ##STR1## wherein: n is 2 or 3;

REFERENCES:
patent: 4306076 (1981-12-01), Nelson
Morton et al, "J. Organic Chem.", vol. 44 (1979) p. 2880.
Aristoff et al, "J. Organic Chem.", vol. 48 (1983) 5341.
Crossley, "Tetrahedron Letters" (1971) p. 3327.
Corey et al, "Tetrahedron Letters" (1973) p. 3091.
Kojima et al, "Tetrahedron Letters" (1978) p. 3743.
Shibasaki et al, "Tetrahedron Letters" (1979) p. 433.

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