Urine testing module and method of collecting urine antigen

Details Urine testing module and method of collecting urine antigen Urine testing module and method of collecting urine antigen

1989-09-25

1991-05-21

Hindenburg, Max

Surgery

Truss

Pad

604317, A61B 500

Patent

active

050166441

ABSTRACT:
A method for testing for biological molecular indicators in urine. Urine is transported through a sample container under pressure to flow through the sample container so that antigens in the urine are collected and bound on antibodies immobilized on the beads to form antigen-antibody complex. The beads are washed to remove cell debris and charged molecules and a specific prelabelled antibody solution is passed through the sample container with the prelabelled antibodies attaching to a receptor site on the captured antigen to form an antibody-antigen-prelabelled antibody sandwich complex. This sandwich complex is washed to remove cell debris and charged molecules and mixed with a color reagent solution which reacts with the prelabelled antibody to produce an color indicating the presence of a specific cancer antigen.

REFERENCES:
patent: 3312221 (1967-04-01), Overment
patent: 4473530 (1984-09-01), Vilk-Real
patent: 4492258 (1985-01-01), Lichtenstein et al.
patent: 4661100 (1987-04-01), Rechsteiner
patent: 4685472 (1987-08-01), Muto

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