Preparation of indoles by cyclization

Details Preparation of indoles by cyclization Preparation of indoles by cyclization

1988-11-14

1990-04-10

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20908, C07B 3710

Patent

active

049162365

ABSTRACT:
Disclosed herein is a preparation process for an indole, which process comprises subjecting an N-(.beta.-hydroxy)-alkylaniline, in the presence of a catalyst and at a super-atmospheric pressure, to a gas-phase catalytic reaction. The present process improves the selectivity of the reaction and the service life of the catalyst.

REFERENCES:
patent: 4376205 (1983-03-01), Matsuda et al.
patent: 4436916 (1984-04-01), Matsuda et al.
patent: 4443615 (1984-04-01), Matsuoka et al.
Article by Takaoka, Accetone, Methyl Ethyl Ketone and Methyl Isobutyl Ketone of May, 1972, Process Economics Program, Stanford Research Institute, Menlo Park, CA.
Article, The Oil and Gas Journal, Jun. 15, 1981, p. 153.
The Encyclopedia of Chemical Technology, vol. 19, p. 64.
MTC-I Chemical Abstracts, 95, 115293b.
MTC-II Chemical Abstracts, 95, 115295d.

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