Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-03-21
1986-01-21
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514317, 514329, 514330, 514913, A61K 31445
Patent
active
045658218
ABSTRACT:
Aqueous humor formation and intraocular pressure in mammals having ocular hypertension or glaucoma may be reduced by topically administering to a hypertensive eye an ophthalmologically acceptable amount of a dopamine antagonist or acid addition salt thereof. A preferred group of dopamine antagonists is the butyrophenones, especially haloperidol, trifluperidol, and moperone. An ophthalmic composition for topically treating glaucoma may comprise an aqueous solution containing 0.01% to 5% by weight of a water-soluble ophthalmologically acceptable acid addition salt of such dopamine antagonist.
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Robinson Douglas W.
The Texas A&M University System
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