N-acylamino acid derivatives and their use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142358, 5142368, 514269, 514363, 514381, 544122, 544141, 544142, 544152, 544316, 548136, 548251, A61K 31535, C07D41312

Patent

active

052409244

ABSTRACT:
An N-acylamino acid derivative of the formula: ##STR1## wherein the substituents are herein defined, or a salt thereof, which is useful as hypotensive drugs.

REFERENCES:
Bolis et al, J. Med. Chem. 1987, 30, 1729-1737.
Haber et al, J. Cardiovascular Pharm., 10 (Supp. 7):554-558, 1987.
Plattner et al. J. Med Chem. 1988:31, 2277-2288.
Denkewatter et al, Progress in Drug Research, 1966, 510-515.
Burger, Medicinal Chemistry 2nd ed, 1960, pp. 565-571, 579-581.
Patent Abstracts Japan, C Field vol. 11, No. 136, 1987, Kokai 61-275258.
Patent Abstracts Japan, C field, vol. 11 No. 349, 1987, Kokai 62-120370.

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