Derivatives of 7-(.alpha.-hydroxy-substituted pyridyl carboxamid

Details Derivatives of 7-(.alpha.-hydroxy-substituted pyridyl carboxamid Derivatives of 7-(.alpha.-hydroxy-substituted pyridyl carboxamid

1975-10-08

1977-07-19

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50136

Patent

active

040368343

ABSTRACT:
Novel 7-(.alpha.-hydroxy-substituted pyridylcarboxamido-.alpha.-phenylacetamido)-3-substituted thiomethyl-.DELTA..sup.3 -cephem-4-carboxylic acid derivatives are disclosed. The compounds of this invention have high water solubility and show excellent antibacterial activities against various strains of Pseudomonas and Proteus.

REFERENCES:
patent: 3843642 (1974-10-01), Jackson et al.
patent: 3946015 (1976-03-01), Goel
patent: 3948903 (1976-04-01), Doub et al.
CA, vol. 81, Teruya et al., p. 536, Abst. 105,537f (1974).

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