Lightly cross-linked hydrogel formed from N-vinyl lactam and hyd

Chemistry of carbon compounds – Miscellaneous organic carbon compounds

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260 63UY, 526264, 526265, C08F 2608

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active

040368149

ABSTRACT:
A copolymeric hydrogel for contact lenses with physiological saline uptake 65-85% is formed from an N-vinyl lactam e.g. N-vinyl-2-pyrrolidone and up to 15% of a hydrophobic comonomer of formula ##STR1## where R.sup.1 is H or C.sub.1 -C.sub.4 alkyl (preferably methyl) X is --O-- or --NH-- and R.sup.2 is aryl, C.sub.1 -C.sub.6 alkyl substituted by aryl or aryloxy, or C.sub.1 -C.sub.6 alkoxy substituted by aryl or aryloxy. Preferably the aryl or aryloxy group contain one or two six-membered carbocyclic aromatic rings; they may be C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, or halogen, substituted. Crosslinking agents used preferably have their two functional groups differing in reactivity e.g. allyl, or 3-allyloxy-2-hydroxypropyl, methacrylates.

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patent: 3532679 (1970-10-01), Steckler
patent: 3629197 (1971-12-01), Stiehl
patent: 3699089 (1972-10-01), Wichterle
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patent: 3787380 (1974-01-01), Stamberger
patent: 3792028 (1974-02-01), Seidermann
patent: 3878175 (1975-04-01), Steckler

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