Precursors of .beta.-lactam antibacterials having soluble side c

Details Precursors of .beta.-lactam antibacterials having soluble side c Precursors of .beta.-lactam antibacterials having soluble side c

1997-07-17

1999-07-13

Marx, Irene

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

435 47, 435 43, C07C 5300

Patent

active

059229071

ABSTRACT:
Disclosed is a process for the synthesis of .beta.-lactam antibacterials using soluble side chain esters in the presence of enzyme acylase. Also disclosed are novel esters useful as reactants in said process.

REFERENCES:
patent: 4340672 (1982-07-01), Kondo et al.
Fernandez-Lafuente, R., et al., Enzyme and Microbial Technology, vol. 19, Jul. 1996, pp. 9-14.

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