Thiodeazapurine derivatives

Details Thiodeazapurine derivatives Thiodeazapurine derivatives

1984-03-16

1986-06-17

Lesmes, George F.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602433, 544117, 544280, 514258, C07D22304, C07D22502, C07D48704

Patent

active

045955301

ABSTRACT:
7-Deazapurine derivatives of the formula: ##STR1## wherein R.sub.1 is hydrogen atom or an acyl group and R.sub.4 and R.sub.5 each is a hydrogen atom or a hydrocarbon residue which may optionally have one or more substituents or R.sub.4 and R.sub.5, together with the adjacent nitrogen atom, from a cyclic amino group are useful as an anti-tumor agent, microbicide or disinfectant.

REFERENCES:
patent: 4435569 (1984-03-01), Nishimura et al.
Journal of Biological Chemistry, 254, p. 3067 (1979)--Novel Mechanism of Post-Transcriptional Modification of TRNA--Okada.
Biochemical and Biophysical Research Communications, P96, p. 313 (1980) Administration of Queuine To Mice Relieves Modified Nucleoside Queuosine Deficiency in Ehrlich Ascites Tumor TRNA--Katze.

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