Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1985-08-08
1988-10-25
Hazel, Blondel
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 857, 435 68, 435811, C07K 1300, A61K 4502, C12P 2100
Patent
active
047805307
ABSTRACT:
Novel IFN.alpha.S51B10 and IFN.alpha.S17H9 of this invention are prepared from BALL-1 cell induced with Sendai virus according to the well known recombinant DNA technique. Further, this invention relates to a DNA encoding interferon .alpha.S51B10 or .alpha.S17H9, a recombinant plasmid enabling an expression of interferon .alpha.S51B10 or .alpha.S17H9 in a host microorganism and a microorganism transformed by the recombinant plasmid. These two IFN.alpha.s have antiviral and anti-tumor activity as other subtypes of IFN.alpha. and are useful as medicines for human and animal.
REFERENCES:
Langer et al., J. Investigative Dermatology, vol. 33, pp. 1285-1365, 1984.
Sato Kosaburo
Tanaka Kentaro
Teraoka Hiroshi
Hazel Blondel
Shionogi & Co. Ltd.
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