4 or 5-(substituted piperazinylalkyl)-2-aminothiazoles as antips

Details 4 or 5-(substituted piperazinylalkyl)-2-aminothiazoles as antips 4 or 5-(substituted piperazinylalkyl)-2-aminothiazoles as antips

1988-05-27

1990-06-19

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514256, 514269, 514274, 514333, 514342, 544295, 544316, 544319, 544333, 544357, 544364, 544369, 544379, 544405, 546256, 546280, A61K 31495, A61K 3144, A61K 31405, C07D41714, C07D40514, C07D40914

Patent

active

049354248

ABSTRACT:
Substituted 2-aminothiazoles are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as dopamine agonists with selectivity for the presynaptic dopamine receptor and are useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.

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patent: 4737500 (1988-04-01), Sorg
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PCT International Search Report PCT/US89/02273.
Farmaco, Ed. Sci., 1986, 41(6), 483-98, Acta Polon. Pharm. XL, NR 2, 1983, pp. 159-170.

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