Diaminopyridines to improve cognition

Details Diaminopyridines to improve cognition Diaminopyridines to improve cognition

1982-02-22

1983-05-31

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3144

Patent

active

043860958

ABSTRACT:
Diaminopyridines improve cognition in aged animals. 3,4-Diaminopyridine is disclosed as a preferred compound to improve the decreased cognitive function which accompanies aging. It is believed that the diaminopyridines improve cognition by affecting nervous system acetylcholine metabolism.

REFERENCES:
Gibson et al., Neuroscience Abstr., 7:187 (1981).
Gibson et al., Fed. Proc., 65 200 (1981).
Drachman et al., Neurobiology of Aging, 1:39 (1981).
Drachman, Neurology, 27-783 (1977).
Lundh et al., Neurol. Neurosurg., Psychiat. 40 1109 (1977).
Agoston et al., Anaesth. 50:383 (1978).
Lundh et al., Neurol. Neurosurg., Psychiat. 42:171 (1979).
Davies et al., Brain Res. 138:385 (1978).
Gibson et al., International Soc. Neurochem. 8-386 (1981).
Arehart-Treichel, Science News, 120:378 (1981).
Gibson et al., Biochem. Pharm. 31:111 (1982).

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