Method for producing amino-2-imidazoline derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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5483315, 5483331, C07D23346

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active

052370720

ABSTRACT:
A method for producing an amino-2-imidazoline derivative comprises contacting an imidazoline sulfonic acid with at least one amine component in the presence of an alcohol-containing liquid medium at conditions effective to form the amino-2-imidazoline derivative.

REFERENCES:
patent: 1912849 (1933-06-01), Kranzlein et al.
patent: 2742481 (1956-04-01), Cain
patent: 2876223 (1957-03-01), Bloom
patent: 3890319 (1975-07-01), Danielewicz et al.
patent: 4210658 (1980-07-01), Durant et al.
patent: 4656291 (1987-04-01), Maryanoff et al.
Clonidine and related compounds, Jarrott, Bevyn, Handbook of Hypertens., 1984, vol. 5, pp. 113-168.
Alpha 2-adrenergic agonists: a newer class of antidiarrheal drug, Dharmsathaphorn, K, Gastroenterology, Sep. 1986, 91, (3) pp. 769-770.
A Convenient Synthesis of Guanidines from Thioureas, Maryanoff et al, J. Org. Chem. (1986), pp. 1882-1884.
Alpha-2-adrenergic modulation of norepinephrine secretion in the perfused rabbit iris-ciliary body, Jumblatt et al, Curr. Eye Res., Jun. 1987, 6(6) pp. 767-777.
Ocular Effects of Selective alpha-adrenergic agents: A new drug paradox?, Mittag, Tom, Ann. Ophthalm. Mar. 1983 15(3) pp. 201-202.
Mechanism of alpha-2-adrenoceptor agonist-induced diuresis Gellai et al, Am J Physiol, Aug. 1988, 255(2 pt 2) pp 317-323.
Clonidine and some bridge analogs; cardiovascular effects and nuclear magnetic resonance data, Timmermans et al, Eur. J. Med. Chem., 1980 (15) pp 323-329.
Alpha 2-adrenergic receptors accelerate Na+/H+ exchange in neuroblastoma X Glioma Cells, Isom et al, J Biol Chem May 15, 1987, 262(14) pp. 6750-6757.
Clonidine:new research in psychotropic drug pharmacology, Fielding et al, Med Res Rev, Spring 1981, 1(1) pp. 97-123.
Renal effects of selective alpha-1 and alpha-2 adrenoceptor agonists in conscious, normotensive rats, Gellai et al, J. Pharmacol. Exp. Ther., Mar. 1987, 240(3) pp. 723-728.
Selective Alpha-2 adrenoceptor agonists alter fluid and electrolyte transport in mammalian small intestine, Fondacaro et al., J. Pharmacol. Exp. Ther., Nov. 1988, 247 (2) pp. 481-486.
Ocular effects of a relatively selective Alpha-2 agonist (UK-14,304-18) in cats, rabbit and monkeys, Burke et al, Curr. Eye Rsch., Sep. 1986, 5(9), pp. 665-676.

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