Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-11-16
1993-08-17
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 58, 5483111, A61K 31415, C07D40506
Patent
active
052369447
ABSTRACT:
Method of treating neoplasms hosting in mammals by administering a C.sub.1-4 alkyl [4-[2-(4-C.sub.1-4 alkylphenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl-thio]pheny l]carbamate. Pharmaceutical compositions containing the same as active ingredient. Compounds used in said method and process for preparing said compounds.
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R. Van Ginckel, et al., Anticancer Research 6:705-708 (1986).
W. Distelmans, et al., Invasion and Metastasis 5:170-184 (1985).
R. Van Ginckel, et al., Eur. J. Cancer Clin. Oncol. 20:99-105 (1984).
G. Gevens, et al., Cancer Research 45:733-742 (1985).
Distelmans Willem H. K. M.
Heeres Jan
Van Ginckel Robert F.
Brust Joseph Paul
Haley Jacqueline
Janssen Pharmaceutica N.V.
Metz Charles J.
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