Novel method for determining cholinesterase activity

Details Novel method for determining cholinesterase activity Novel method for determining cholinesterase activity

1987-04-14

1989-08-29

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

560 70, C12Q 146

Patent

active

048617130

ABSTRACT:
This invention relates to a method for determination of cholinesterase activity, characterized by using, as a substrate, a choline derivative represented by the general formula (I): ##STR1## wherein X is a halogen atom; Y.sub.1 is a hydroxyl group as a substituent in the 2- or 5-position; and Y.sub.2 is a hydroxyl group as a substituent in the 3-position.
The determination method of this invention permits easy and simple determination of cholinesterase activity, and is very useful as a determination method for clinical examinations for the purpose of determining cholinesterase in serum.

REFERENCES:
patent: 4565780 (1986-01-01), Motonaga et al.
patent: 4717659 (1988-01-01), Kuroiwa
Journal of Chromatography, vol. 260, 1983, pp. 193-199, S. Clausen et al., "Separation of Aromatic Choline Esters by High-Performance Liquid Chromatography".

Affiliated with

Also associated with

Rating

Novel method for determining cholinesterase activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel method for determining cholinesterase activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel method for determining cholinesterase activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2237945