Bifunctional isothiocyanate derived thiocarbonyls as ligands for

Details Bifunctional isothiocyanate derived thiocarbonyls as ligands for Bifunctional isothiocyanate derived thiocarbonyls as ligands for

1994-06-30

1996-06-18

Wu, Shean

Organic compounds -- part of the class 532-570 series

Organic compounds

Radioactive metal containing

534 10, 5303913, 5303915, C07C33706, C07C33522, A61K 3514

Patent

active

055278850

ABSTRACT:
This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, isothiocyanate derived thiocarbonyls for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.

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