Thieno[2,3-d]pyrimidine derivatives

Details Thieno[2,3-d]pyrimidine derivatives Thieno[2,3-d]pyrimidine derivatives

1973-05-07

1976-05-18

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602564F, 2603323R, 2602565R, 2603305, 2602472A, 260329AM, 2603322R, 424251, 2602477R, 2602477V, 2602477Z, C07D49504

Patent

active

039577830

ABSTRACT:
Novel thienopyrimidine derivatives which have excellent pharmacological uricosuric activity are prepared by reacting a thiophene derivative with cyanic acid or a salt thereof, urea or a reactive ester of carbamic acid. If desired, alkylated, halogenated or nitrated thienopyrimidine derivatives are produced by reacting thienopyrimidine derivatives with an alkylating, halogenating or nitrating agent, respectively.

REFERENCES:
patent: 3830813 (1974-08-01), Woitum et al.
Robba et al., Chemical Abstracts, V. 70, 37,767b (1969).
Robba et al., Chemical Abstracts, V. 69, 27,365j (1968).
Robba et al., Chemical Abstracts, V. 69, 96,635j (1968).
Sauter, Chemical Abstracts, V. 69, 96,647q (1968).
Gronowitz et al., Chemical Abstracts, V. 70, 87,745p (1969).
Manhas et al., Chemical Abstracts, V. 71, 101,801h (1969).
Schweizer et al., Chemical Abstracts, V. 72, 90,498g (1970).
Manhas et al., Chemical Abstracts, V. 76, 107846b, (5/8/72).

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