Antibiotic compound

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 78, 435907, C12D 914

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active

041629388

ABSTRACT:
A novel anthracycline antibiotic designated rudolphomycin is produced by fermentaion of Actinosporangium sp. ATCC 31127 and isolation of the new antibiotic free of substances co-produced therewith. Rudolphomycin and its pharmaceutically acceptable salts exhibit antimicrobial activity and inhibit the growth of mammalian tumors.

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Eckardt et al., "Some red hydroxyquinone dyes from a Streptomyces strain:galirubinone and galibin", Chem. Abstracts, vol. 68, 3896g (1966).
Eckardt, "Red antibiotics from actinomycetes Identification of a series of anthracyclinone pigments from Streptomyces galilscus strain JA 3043, (galirubin and galirubinone), Chem. Abstracts, vol. 67, pp. 9014, 9015, Abs. #90573z.
Asheshov, "Rutilantin:an Antibiotic Substance with Antiphage Activity", Brochem. J., vol. 81, (1961) pp. 101-104.
Fleck et al., "Screening, Fermentation, Isoluton, and Characterization of Trypanomycin, a New Antibiotic", Antimicrobial Agents and Chemotherapy, vol., No. 5, (1972), pp. 385-391.
Gottlieb et al., Antibiotics, vol. 1, Springer-Verlag New York, Inc., N.Y., N.Y. (1967) pp. 190-210.
Information Bulletin, No. 10 International Center of Information of Antibiotics, in collaboration with WHO, Dec. 1972, Belgium.

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