Combination of an opioid antagonist and a selective serotonin re

Details Combination of an opioid antagonist and a selective serotonin re Combination of an opioid antagonist and a selective serotonin re

1999-07-21

2000-06-06

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514282, 514321, 514410, 514649, 514651, 514657, A61K 31495, A61K 3144, A61K 31445, A61K 3140, A61K 31135

Patent

active

060719184

ABSTRACT:
The invention relates to a method of treating alcoholism and alcohol dependence in a mammal comprising administering to the mammal a therapeutically effective amount of a synergistic combination of: (i) at least one opioid antagonist, and (ii) at least one selective serotonin reuptake inhibitor. The invention also relates to compositions and kits containing the same.

REFERENCES:
patent: 5817665 (1998-10-01), Dante
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T. W. Rall, in: Goodman and Gilman's The Pharmacological Basis of Therapeutics, A. G. Gilman et al. 8.sup.th Edition, Chap. 17, 378-379.

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