Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-09-26
1987-03-31
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549467, 549468, A61K 3134, C07D30785
Patent
active
046543651
ABSTRACT:
The invention relates to novel substituted 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, their derivatives and their salts. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydrocephalus, post-operative brain injury trauma, edema due to cerebral infections and various brain concussions.
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Cragoe, Jr. Edward J.
Woltersdorf, Jr. Otto W.
Caruso Charles M.
Dentz Bernard I.
Jiles Henry R.
Merck & Co. , Inc.
Pfeiffer Hesna J.
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