Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
2000-02-16
2000-09-05
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514566, A61K 31195
Patent
active
061143871
ABSTRACT:
A solid pharmaceutical composition for the oral administration of chelating agents to an individual consists essentially of: at least 100 milligrams of ethylenediaminetetraacetic acid (EDTA) or a molar equivalent amount of pharmaceutically acceptable salts or hydrated salts of EDTA, at least 75 milligrams of N-acetyl-L-cysteine, and an appropriate amount of at least one pharmaceutical formulating agent.
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Banner, W., et al, "Experimental Chelation Therapy in Chromium, Lead, and Boron Intoxication With N-Acetylcysteine and Other Compounds", Toxicology and Applied Pharmacology, 1986, vol. 83, pp. 142-147.
Peters, Henry, et al., "Turkish Epidemic Hexachlorobenzene Porphyria: A 30-Year Study", Annals of the New York Academy of Sciences, (Mechanisms of Chemical--Induced Porphyrinopathies), 1987, vol. 514, pp. 183-189.
Brumas, V., et al., "Can N-Acetyl-L-cysteine Affect Zinc Metabolism When Used as a Paractamol Antidote", Agents Actions, 1992, vol. 36, pp. 278-188.
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