Methods of detecting T-cell activation and treating disorders as

Details Methods of detecting T-cell activation and treating disorders as Methods of detecting T-cell activation and treating disorders as

1999-06-25

2000-09-05

Chan, Christina Y.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 29, 5303871, 4241541, 4241301, G01N 3353, G01N 33555, G01N 33567, G01N 33542, C12Q 102

Patent

active

061141291

ABSTRACT:
Methods of detecting activated T-cells involve monitoring levels of MUC-1 mucin expression at the protein and/or mRNA level. Compositions for modulating immune function contain compounds that modulate the expression or function of MUC-1. Methods of treating disorders associated an inappropriate state of T-cell activation involve contacting a T-cell with a compound containing an inhibitor of MUC-1 expression or function.

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