Preparation of fluorinated anilines

Details Preparation of fluorinated anilines Preparation of fluorinated anilines

1977-11-30

1979-03-20

Douglas, Winston A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260465D, 260465E, 260575, 560 18, 560 19, 560 22, 560 46, 560 47, 560142, C07C 8511

Patent

active

041453646

ABSTRACT:
Fluorinated anilines, especially p-fluoroaniline and 2,4-difluoroaniline, are prepared by treating aromatic azides with anhydrous hydrogen fluoride. The aromatic azides, in turn, are prepared from the corresponding anilines by treatment with nitrous acid or salt thereof and an alkali metal azide in the presence of a mineral acid, and in an aqueous-nonaqueous, two-phase environment.

REFERENCES:
bamberger, "Ann.", 424, pp. 233-263 (1921).
Heller et al., "Nature", 168, pp. 909-910 (1951).
Patrick et al., "J. Org. Chem.", 39(12), pp. 1758-1761 (1974).
Bachrach et al., "Organic Synthesis", IV, pp. 74-78 (1954).
Finger et al., "J. Am. Chem. Soc.", 78, pp. 6034-6037 (1956).

Affiliated with

Also associated with

Rating

Preparation of fluorinated anilines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of fluorinated anilines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of fluorinated anilines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-220640