Epidermal growth factor receptor targeted molecules for treatmen

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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435 697, 536 234, A61K 3800

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active

056144881

ABSTRACT:
The invention features a method for treating a patient having inflammatory arthritis, the method includes administering to the patient a molecule which is capable of specifically binding to an epidermal growth factor receptor expressed on a cell of the patient which contributes to the inflammatory arthritis of the patient, the molecule being capable of decreasing the viability of the cell.

REFERENCES:
patent: 4468382 (1984-08-01), Bacha et al.
patent: 4545985 (1985-10-01), Pastan et al.
patent: 4675382 (1987-06-01), Murphy
patent: 4946778 (1990-08-01), Ladner et al.
Chaudhany et al PNAS 84:4538-4542 1987.
Yocum et al Abstract D98, p. S150, 54th Annual Meeting American Collige of Rheumatology Seattle, WA Oct. 1990.
Shaw et al., "Cytotoxic Properties of DAB.sub.486 EGF and DAB.sub.389 EGF, Epidermal Growth Factor (EGF) Receptor-targeted Fusion Toxins", The Journal of Biological Chemistry, 266(31):21118-21124, (1991).
Williams et al., "Structure/Function Analysis of Interleukin-2-Toxin (DAB.sub.486 -IL-2)", The Journal of Biological Chemistry, 265(2):11885-11889, (1990).
Johnson et al., U.S. Department of Health and Human Services, U.S. Serial No. 401, 412.
Huse et al., Science 246:1275-1281, 1989.
Case et al., Proc. Natl. Acad. Sci. USA 86:287-291, 1989.
Zvaifler et al., The American Journal of Medicine 85:12-17, 1988.
Defeo-Jones et al., Molecular and Cellular Biology, 8:2999-3007, 1988.
Stunkel et al., Immunology 64:683-689, 1988.
Williams et al., Nucleic Acids Research 16:10453-10467, 1988.
Calderwood et al., Proc. Natl. Acad. Sci. USA 84:4364-4368, 1987.
Hwang et al., Cell 48:129-136, 1987.
Colombatti et al., The Journal of Biological Chemistry, 261:3030-3035, 1986.
Holoshitz et al., The Lancet 2:305-309, 1986.
Pappenheimer, Ann. Rev. Biochem. 46:69-94, 1977.
Uchida et al., The Journal of Biological Chemistry 248:3838-3844, 1973.
Hertel et al., The Journal of Biological Chemistry 260:12547-12553, 1985.
Moya et al., The Journal of Cell Biology 101:548-559, 1985.
Hoch et al., Proc. Natl. Acad. Sci. USA 82:1692-1696, 1985.
Amann et al., Gene 40:183-190, 1985.
Gray et al., Proc. Natl. Acad. Sci. USA 81:2645-2649, 1984.
Beguinot et al., Proc. Natl. Acad. Sci. USA 81:2384-2388, 1984.
Deleers et al., FEBS 160:82-86, 1983.
Maassen et al., Euro. J. Biochem. 134:327-330, 1983.
Beck et al., Gene 19:327-336, 1982.
Moynihan et al., Infection and Immunity, 32:575-582, 1981.
Uchiyama et al., The Journal of Immunology 126:1393-1397, 1981.
Trentham et al., The Journal of Experimental Medicine 146:857-868, 1977.

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