Inhibitors of cell-medicated disorders

Details Inhibitors of cell-medicated disorders Inhibitors of cell-medicated disorders

1994-02-14

1998-06-09

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

514491, 514492, 424650, A61K 3128

Patent

active

057634807

ABSTRACT:
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or Tl-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or Tl-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and Tl, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well.

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