Triterpene derivatives with immunosuppressant activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549268, A61K 31365, C07D49302

Patent

active

057634785

ABSTRACT:
The compounds of Formula I ##STR1## are useful as immunosuppressive agents.

REFERENCES:
Abreu et al., Phytochemistry, vol. 29, No. 7, pp. 2257-61, 1990.
Abreu, et al., "A Nor-Triterpenoid from Lophanthera Lactescens.", Phytochemistry, vol. 29(7), pp. 2257-2261, 1990.
Verheugen, J. A. H., et al., "Enhancement of Calcium Signaling and Proliferation Responses in Activated Human T Lymphocytes", Cell Calcium, vol. 21(1), pp. 1-17, (1997).

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