Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1996-09-12
1998-06-09
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435147, 435155, 435157, 435160, 435174, 435189, 435190, 4352523, 43525411, 43525422, 536 232, C12P 716, C12P 726, C12N 904, C12N 1553
Patent
active
057632367
ABSTRACT:
The present invention provides a novel secondary alcohol dehydrogenase useful for the synthesis of optically active alcohol and DNA encoding said enzyme. A microorganism belonging to genus Candida was found to produce a novel secondary alcohol dehydrogenase with a high stereochemical specificity. Using said enzyme, optically active alcohols were prepared, and by cloning of DNA encoding said enzyme, the base sequence of said DNA was determined. By providing a novel secondary alcohol dehydrogenase with a high stereochemical specificity and the gene encoding said enzyme, an efficient production of optically active alcohols became possible.
REFERENCES:
patent: 5200335 (1993-04-01), Hummel et al.
patent: 5342767 (1994-08-01), Wong et al.
Gwynne, D. I., et al., Gene, vol. 51, "Comparison of the cis-acting regions of two coordinately controlled genes involved in ethanol utilization in Aspergillus nidulans", pp. 205-216, 1987.
Shain, D. H., et al., Molecular and General Genetics, vol. 232, "Evolution of the alcohol dehydrogenase (ADH) genes in yeast: characterization of a fourth ADH in Kluyveromyces lactis", pp. 479-488, 1992.
Ladriere, J.-M., Biochimica et Biophysica Acta, vol. 1173, "Sequences of a gene coding for a cytoplasmic alcohol dehydrogenase from Kluyveromyces marxianus ATCC 12424", pp. 99-101, 1993.
II'Chenko, A. P., et al., Biokhimiya, vol. 59, "Purification and some properties of alcohol oxidase from the yeast Yarrowia lipolytica H-222", pp. 1312-1319, 1994.
Hommel, R. K., et al., Applied Microbiology and Biotechnology, vol. 40, "The inducible microsomal fatty alcohol oxidase of Candida (Torulopsis) apicola", pp. 729-734, 1994.
Clark, D.S., et al., Bioorganic & Medicinal Chemistry Letters, vol. 4, "Enantioselective oxidation of 2-methyl-1-butanol by alcohol oxidase from methylotropic yeasts", pp. 1745-1748, 1994.
Journal of Biological Chemistry, vol. 268, No. 11, pp. 7792-7798, Apr. 15, 1993, David W. Green, et al., "Inversion of the Substrate Specificity of Yeast Alcohol Dehydrogenase".
Journal of Organic Chemistry, vol. 57, No. 5, pp. 1526-1566, Feb. 28, 1992, Curt W. Bradshaw, et al., "A Pseudomonas sp. Alcohol Dehydrogenase with Broad Substrate Specificity and Unusual Stereospecificity for Organic Synthesis".
Kawada Naoki
Kojima Tomoko
Matsuyama Akinobu
Yamamoto Hiroaki
Daicel Chemical Industries Ltd.
Moore William W.
Wax Robert A.
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