Method for restoring depleted purine nucleotide pools

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 47, 514 48, 536 23, A61K 3170

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active

045754985

ABSTRACT:
A method of increasing the rate of repletion of purine nucleotide pools in tissue deficient in the nucleotides, which comprises administering to a human or animal a therapeutically effect amount of 5-amino-4-imidazolecarboxamide riboside, 5-amino-4-imidazolecarboxamide, or a pharmaceutically acceptable salt thereof sufficient to increase the rate of the repletion is disclosed along with pharmaceutical compositions useful for carrying out the method of the invention.

REFERENCES:
patent: 3332935 (1967-07-01), Yamazaki et al.
patent: 3803126 (1974-04-01), Rousseau et al.
Toninello, et al., "Chem. Abst.", vol. 80, 1974, P 57898(e), 1973.
Atsuta et al., "Chem. Abst.", vol. 97, P. 124724(m), 1982.
Hasegawa et al. "Chem. Abst.", vol. 100, P. 3950(d), 1984 (effective date, 1982).
Cohen et al., "Chem. Abst.", vol. 100 P. 3958(n), 1984 (effective date, 1983).

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