Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1983-07-21
1986-03-11
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 47, 514 48, 536 23, A61K 3170
Patent
active
045754985
ABSTRACT:
A method of increasing the rate of repletion of purine nucleotide pools in tissue deficient in the nucleotides, which comprises administering to a human or animal a therapeutically effect amount of 5-amino-4-imidazolecarboxamide riboside, 5-amino-4-imidazolecarboxamide, or a pharmaceutically acceptable salt thereof sufficient to increase the rate of the repletion is disclosed along with pharmaceutical compositions useful for carrying out the method of the invention.
REFERENCES:
patent: 3332935 (1967-07-01), Yamazaki et al.
patent: 3803126 (1974-04-01), Rousseau et al.
Toninello, et al., "Chem. Abst.", vol. 80, 1974, P 57898(e), 1973.
Atsuta et al., "Chem. Abst.", vol. 97, P. 124724(m), 1982.
Hasegawa et al. "Chem. Abst.", vol. 100, P. 3950(d), 1984 (effective date, 1982).
Cohen et al., "Chem. Abst.", vol. 100 P. 3958(n), 1984 (effective date, 1983).
Holmes Edward W.
Swain Judith L.
Brown Johnnie R.
Duke University
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