Cephalosporanic acid derivatives

Details Cephalosporanic acid derivatives Cephalosporanic acid derivatives

1984-01-30

1984-11-20

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C07D50134

Patent

active

044839812

ABSTRACT:
Novel syn isomers of 7-amino-thiazolyl-acetamido-3-acetoxymethyl-cephalosporanic acid derivatives of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of --CN, --CONH.sub.2 and --COOR.sub.1 ', R.sub.1 ' is selected from the group consisting of alkyl of 1 to 3 carbon atoms, hydrogen, alkali metal, alkaline earth metal, ammonium, magnesium and a non-toxic, pharmaceutically acceptable organic amine, A is selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, ammonium, magnesium and a non-toxic, pharmaceutically acceptable organic amine, R' and R" are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms with the ##STR2## in the syn position with the proviso that when R.sub.1 is --COOR.sub.1 ' and R.sub.1 ' is hydrogen, A is hydrogen and when R.sub.1 is --COOR.sub.1 ' and R.sub.1 ' is an alkali metal, alkaline earth metal, magnesium, ammonium or an organic amine, A is an alkali metal, alkaline earth metal, magnesium, ammonium or an organic amine having antibiotic properties and novel intermediates and processes.

REFERENCES:
patent: 3971778 (1976-07-01), Cook et al.
patent: 4007174 (1977-02-01), Laundon
patent: 4098888 (1978-06-01), Ochiai et al.
patent: 4103084 (1978-07-01), Bradshaw et al.
patent: 4152432 (1979-05-01), Heymes et al.
patent: 4166115 (1979-09-01), Takaya et al.

Affiliated with

Also associated with

Rating

Cephalosporanic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cephalosporanic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephalosporanic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2189956