Therapeutically active fluoro substituted benzimidazoles

Details Therapeutically active fluoro substituted benzimidazoles Therapeutically active fluoro substituted benzimidazoles

1993-10-08

1995-08-15

Fan, Jane

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546271, C07D40112, A61K 3144

Patent

active

054419689

ABSTRACT:
The novel compounds of the formulas I and I' ##STR1## wherein F is in 5 or 6 position and ##STR2## wherein in both formulas R is the group --CH.sub.2 OCOOR.sup.1, wherein R.sup.1 is a straight or branched alkyl containing 1-6 carbon atoms or benzyl, or R.sup.1 is the group ##STR3## wherein n is 1-6 and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient, and the use of the compounds in medicine.

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patent: 4255431 (1981-03-01), Junggren
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patent: 5021433 (1991-06-01), Alminger et al.
patent: 5021433 (1991-06-01), Alminger et al.
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Derwent 87-294449/42, 1987.

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