4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof

Details 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof

1977-06-20

1980-02-05

Wheeler, David

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546155, A61K 3147

Patent

active

041873092

ABSTRACT:
Disclosed are compounds which are 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof, e.g., 1-allyl-6,7-dimethoxy-4-hydroxy-2-quinolinone-3-carboxylic acid, useful as anti-allergic agents, and prepared by hydrolysis of the corresponding carboxylic acid esters.

REFERENCES:
patent: 3772305 (1973-11-01), Hellerbach
patent: 3960868 (1976-06-01), Ferrini et al.
patent: 4107310 (1978-08-01), Allais et al.
patent: 4119720 (1978-10-01), Hardtmann
Brown, "Australian J. Chem.", (1954), vol. 8, pp. 348-377.
McCorkindale, Tetrahedron, (1961), vol. 14, pp. 223-229.
Brown, Aust. J. of Chem., vol. 8, 1955, pp. 121-124.
Asahina et al., Berich. Deutschen Chem. Gessellschaft, vol. 63, 1930, p 2052ff.
Grundon et al., Source not available, (1955), pp. 4284-4290.
Mitscher et al., Heterocycles, vol. 3, No. 11, (1975), pp. 913--919.
Coutts et al., J. Chem. Soc., (1962), 2518-2521 C.A. vol. 57:5891(b) provided.

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